XtaLAB MM007-HF

The XtaLAB MM007-HF system includes a VariMax optic coupled to the MicroMax-007 HF rotating anode generator. The system provides the best balance between outstanding performance for a wide range of crystal types and cost of ownership. The MicroMax-007 HF is the most popular microfocus rotating anode generator because of its proven reliability and performance. When coupled with VariMax optics, the MicroMax-007 HF provides brilliance equaling the very best competitive products with a small focal spot side. Moreover, the MicroMax-007 HF rotating anode generator offers two ports and can be equipped with detector systems on each. Alternatively, one port can be configured for biological SAXS experiments.

HPC Detector

The XtaLAB MM007HF system is coupled with a Hybrid Photon Counting (HPC) detector, such as the HyPix-6000 or PILATUS3 R 200K hybrid photon counting detector (HPC). HPC detectors are ideal for this type of source because they are photon counting detectors that directly detect X-ray photons without the need the intermediate step of converting X-ray photons to light with a phosphor, because they have high dynamic range and fast readout speed, and because they have extremely low noise. Additionally, HPC detectors have an ideal point spread function of a single pixel. These combined features, along with shutterless data collection, means that you can collect more accurate data faster. As a result, the XtaLAB MM007HF system offers outstanding performance for macromolecular experiments.

Dual Port Capability

The XtaLAB MM007HF system offers two ports, allowing you to configure a system with dual single crystal ports or you can configure the second port with a small angle X-ray scattering system, such as the BioSAXS (link to BX2000 page). Thus, the versatility offered with two ports provides an efficient way to expand your structural biology program.

Features

  • True microfocus rotating anode X-ray sources with outstanding beam stability
  • Robust direct-drive anode provides extended anode and filament lifetimes
  • Increased uptime and ease of use with pre-aligned and pre-aged filaments
  • Your choice of VariMax┬Ö confocal double-bounce optics for better spectral purity and beam size to match your sample types
  • Four-circle goniometer to provide completeness and redundancy for your data sets
  • HPC detector with single pixel point spread function and true shutterless data collection
  • HKL-3000R for instrument control, data processing and structure solution
  • Dual ports allow for dual detectors or dual crystallography and SAXS ports, with NO compromise in beam intensity
  • Dual wavelength option - for in-house phasing or dual macro- and small molecule capabilities
X-ray generator
Maximum power 1.2 kW
Voltage 20-60 kV, in 1 kV steps
Current 10-30 mA, in 1 mA steps
HV stability┬╣ ±0.015%
Power requirements 3-phase 200/220 VAC, 12 A
Anode assembly
Available targets Cu, Cr, Mo, Co
Diameter 99 mm
Rotation speed 9000 rpm
Drive mechanism Direct drive
Vacuum seal Low-torque magnetic fluid
Shaft bearing material Ceramic ball bearing
Water seal Mechanical
Tube tower assembly
X-ray window 0.2 mm thick beryllium
Available ports 2
Shutter type High-speed rotary, one per port
Vacuum Integrated turbo-molecular pump
X-ray source data
Filament W, annealed and pre-aligned
Take-off type Horizontal point focus
Effective size at 6° take-off angle 0.07 mm circle for Cu, Cr and Co
0.15 x 0.1 mm ellipse for Mo

¹ For a ±10% variation in line voltage and ±5% change in ambient temperature between 10°C and 25°C

Specification
Optic
Value
Focal spot size (μm) all optics φ = 70
Power (kW) all optics 1.2
Beam size at sample (μm) VariMax HF 208
VariMax HF Arc)Sec 189
VariMax VHF 100
VariMax VHF Arc)Sec 87
Divergence (mR) VariMax HF 4.8
VariMax HF Arc)Sec 4.8
VariMax VHF 10.0
VariMax VHF Arc)Sec 10.0
Flux at φ = 100 μm (photons/sec) VariMax HF 6.13 x 108
VariMax HF Arc)Sec 8.16 x 108
VariMax VHF 1.68 x 109
VariMax VHF Arc)Sec 1.93 x 109
Fluence (photons/sec/mm2) VariMax HF 7.80 x 1010
VariMax HF Arc)Sec 1.04 x 1011
VariMax VHF 2.14 x 1011
VariMax VHF Arc)Sec 2.56 x 1011
Brilliance (photons/sec/mm2/mR2) VariMax HF 3.39 x 109
VariMax HF Arc)Sec 4.51 x 109
VariMax VHF 2.14 x 109
VariMax VHF Arc)Sec 2.56 x 109
Rigaku Oxford Diffraction now offers the HyPix-6000HE Hybrid Photon Counting (HPC) detector. Like all HPCs, the HyPix-6000HE offers direct X-ray photon counting, single pixel point spread function and extremely low noise. The HyPix-6000HE HPC offers a small pixel size of 100 microns, which allows you to better resolve reflections for long unit cells as well as improving reflection profile analysis. The HyPix-6000HE has a high frame rate of 100 Hz, as well as a unique Zero Dead Time mode providing the ultimate in error-free shutterless data collection.
  • Direct photon counting with no phosphor blooming
  • Single pixel point spread function
  • 100 μm x 100 μm pixel size
  • Extremely low noise
  • Frame rate of 100 Hz
  • Electronically gateable
  • Radiation tolerant design
The PILATUS3 R 200K is a hybrid photon counting (HPC) detector designed to achieve the best possible data quality for diffraction experiments. HPC detectors are direct-detection, single-photon counting devices that have essentially no noise and high sensitivity. Moreover, the high dynamic range excellent DQE characteristics for the PILATUS3 R 200K means that they it is well suited for accurately measuring weak reflections alongside very strong reflections - overload corrections and separate scans for weak and strong data are not necessary. The readout time for the PILATUS3 R 200K is 7 msec readout speed, making it capable of true shutterless data collection, thus removing errors associated with shutter open/close and goniometer start/stop events. HPC detectors have revolutionized the way data are collected at synchrotrons and the PILATUS3 R detectors bring those same capabilities to collect the best possible data at home.
Detector PILATUS3 R 200K
Active area 83.8 mm x 70.0 mm
SensorReverse-biased silicon diode array
Dynamic quantum efficiency (Cu-Kα; Mo-Kα)> 98%; > 76%
Dynamic range20-bits
Counting rate per pixel2 x 10⁶ X-ray photons/sec
Readout speed7 msec
Maximum frame rate20 Hz
Point-spread function1 pixel
CoolingAir-cooled
Humidity controlNitrogen or dry air flow
Pixel size172 μm x 172 μm
The PILATUS3 R 300K is a hybrid photon counting (HPC) detector that is desirable by labs who desire the benefits offered by PILATUS detectors combined with 4-circle goniometers, but prefer a larger active area. HPC detectors are direct-detection, single-photon counting devices that have essentially no noise and high sensitivity. Moreover, the high dynamic range excellent DQE characteristics for the PILATUS3 R 300K means that they it is well suited for accurately measuring weak reflections alongside very strong reflections - overload corrections and separate scans for weak and strong data are not necessary. The readout time for the PILATUS3 R 300K is 7 msec readout speed, making it capable of true shutterless data collection, thus removing errors associated with shutter open/close and goniometer start/stop events. HPC detectors have revolutionized the way data are collected at synchrotrons and the PILATUS3 R detectors bring those same capabilities to collect the best possible data at home.
Detector PILATUS3 R 300K
Active area 83.8 mm x 106.5 mm
SensorReverse-biased silicon diode array
Dynamic quantum efficiency (Cu-Kα; Mo-Kα)> 98%; > 76%
Dynamic range20-bits
Counting rate per pixel1 x 10⁷ X-ray photons/sec
Readout speed7 msec
Maximum frame rate20 Hz
Point-spread function1 pixel
CoolingAir-cooled
Humidity controlNitrogen or dry air flow
Pixel size172 μm x 172 μm
The PILATUS3 R 1M is a hybrid photon counting (HPC) detector that provides the best balance between large active area and affordability. HPC detectors are direct-detection, single-photon counting devices that have essentially no noise and high sensitivity. Moreover, the high dynamic range excellent DQE characteristics for the PILATUS3 R 1M means that they it is well suited for accurately measuring weak reflections alongside very strong reflections - overload corrections and separate scans for weak and strong data are not necessary. The readout time for the PILATUS3 R 1M is 7 msec readout speed, making it capable of true shutterless data collection, thus removing errors associated with shutter open/close and goniometer start/stop events. HPC detectors have revolutionized the way data are collected at synchrotrons and the PILATUS3 R detectors bring those same capabilities to collect the best possible data at home.
Detector PILATUS3 R 1M
Active area 168.7 mm x 179.4 mm
SensorReverse-biased silicon diode array
Dynamic quantum efficiency (Cu-Kα; Mo-Kα)> 98%; > 76%
Dynamic range20-bits
Counting rate per pixel1 x 10⁷ X-ray photons/sec
Readout speed7 msec
Maximum frame rate10 Hz
Point-spread function1 pixel
CoolingClosed circuit water cooling
Humidity controlNitrogen or dry air flow
Pixel size172 μm x 172 μm
The EIGER R 1M is a new generation of hybrid photon counting (HPC) detector that combines continuous readout, unrivaled dynamic range and small pixels. HPC detectors are direct-detection, single-photon counting devices that have essentially no noise and high sensitivity. The EIGER R series is the latest generation of HPC detectors that feature auto-summation, which extends their digital counting ability up to 32-bits, or more than 4.2 billion counts, per pixel. Moreover, the EIGER R 1M delivers these high count rates with continuous readout, achieving duty cycles greater than 99%. The EIGER R 1M detectors have small (75 μm) pixels with a single pixel point spread function to provide superior resolving power for reflections from samples with long unit cells, like macromolecules. In general, one can collect at sample-to-detector distances that are 20 - 30% shorter than those used for CCDs or PILATUS detectors. With this state of the art EIGER R 1M detector, you can unlock the true potential of your laboratory instrument.
Detector EIGER R 1M
Active area 77.2 mm x 79.9 mm
SensorReverse-biased silicon diode array
Dynamic quantum efficiency (Cu-Kα)> 97.9%
Dynamic range32-bits
Counting rate per pixel5 x 10⁸ X-ray photons/sec/mm²
Readout speedContinuous readout (4 μs dead time)
Maximum frame rate10 Hz
Point-spread function1 pixel
CoolingAir cooled
Humidity controlNitrogen or dry air flow
Pixel size75 μm x 75 μm
The EIGER R 4M is a new generation of hybrid photon counting (HPC) detector that combines exceptional data collection efficiency and resolving power with an active area rivaling that of CCDs and imaging plate detectors. HPC detectors are direct-detection, single-photon counting devices that have essentially no noise and high sensitivity. The EIGER R series is the latest generation of HPC detectors that feature auto-summation, which extends their digital counting ability up to 32-bits, or more than 4.2 billion counts, per pixel. Moreover, the EIGER R 4M delivers these high count rates with continuous readout, achieving duty cycles greater than 99%. The EIGER R 4M detector have small (75 μm) pixels with a single pixel point spread function to provide superior resolving power for reflections from samples with long unit cells, like macromolecules. In general, one can collect at sample-to-detector distances that are 20 - 30% shorter than those used for CCDs or PILATUS detectors. With this state of the art EIGER R 4M detector, you can unlock the true potential of your laboratory instrument.
Detector EIGER R 4M
Active area 155.2 mm x 162.5 mm
SensorReverse-biased silicon diode array
Dynamic quantum efficiency (Cu-Kα)> 97.9%
Dynamic range32-bits
Counting rate per pixel5 x 10⁸ X-ray photons/sec/mm²
Readout speedContinuous readout (4 μs dead time)
Maximum frame rate10 Hz
Point-spread function1 pixel
CoolingAir cooled
Humidity controlNitrogen or dry air flow
Pixel size75 μm x 75 μm

Graduate Student, Eric Rosenberg, using the MM007/AFC11/P200 at Yale University shares his views of working with Rigaku's scientific staff:

I collected a sulphur SAD data set on our home source using copper K-alpha radiation; these types of data sets are notorious for being difficult to process, but I recalled that a Rigaku application scientist that visited my university, Pierre, stated that he has had luck processing many in the past. I reached out to Pierre asking for some guidance in how to handle my data so that I could solve my protein's structure, and was met with a prompt reply. Pierre was incredibly helpful with his suggestions, very polite, and even seemed personally interested in my work, following up with me a few days later. With his advice, I was able to successfully solve the structure of my protein, which I plan on publishing in my next manuscript. I'm very thankful for Pierre's help, and for Rigaku's customer service in general!"
The 800 Series Cryostream is the most robust, efficient and user-friendly liquid nitrogen based low temperature system available today. Specific features include a superior laminar flow system, meaning virtually zero risk of icing, extremely quiet running and a fast-start system resulting in a cool-down time to 100K of just 20 minutes.
The Oxford Cobra is the non-liquid nitrogen Cryostream. Combining the efficiency of a Cryostream with the advantages of a non-liquid system, the Cobra offers the ultimate solution for both macromolecular and small molecule crystallography.
The Rigaku PlateMate is a simple, inexpensive tool for rapid screening of crystals within crystallization plates. The PlateMate supports several different SBS format crystallization plates, though best results are observed using X-ray compatible plates. The PlateMate is quickly installed on Rigaku 4-circle AFC11 partial chi and non-inverted phi goniometers by virtue of the standard IUCr goniometer mount fitting.

(Requires partial chi option for CCD and PILATUS systems. IP systems may require a camera repositioning kit to modify camera angle for proper viewing of crystallization wells)

ACTOR is a proven commercial solution for automating routine crystal screening and data collection at both synchrotron beam lines and home laboratories. Compatible with almost any goniometer and detector combination, the ACTOR eliminates much of the physical handling of samples required during crystal screening and data collection.
The EZ Aligner tool allows for safe and remote alignment for VariMax or OptiSAXS optics. As the name implies, the EZ Aligner makes optimization of beam intensities an easy task. Simply set up your pin diode and pinhole, then use the EZ Aligner remote to optimize the beam from a safe place outside the radiation enclosure. Each EZ Aligner remote produces a radio signal strong enough to penetrate enclosure material or from another room. The EZ Aligner kit includes a remote control that communicates to 4 motors attached to optic micrometers to adjust optic rotation and translation.
RigakuRemote offers the ability to remotely monitor the status of a single crystal X-ray system from anywhere you can get an internet connection. It provides real-time updates of the state of your instrumentation, including video of the crystal and enclosure. Also included are current information about the scans being collected, and a JPEG view of the last diffraction image collected.